A Unit of Charles Viollette Research Institute


By-products from agro-food industry contain still a broad range of bioactive compounds such as lipids, phytochemicals, pharmaceutics, flavors, fragrances and pigments which can be valorized by selective extraction. Plant extracts are widely used in the food, pharmaceutical and cosmetics industries. Extraction techniques have been widely investigated to obtain such valuable natural compounds from plants for commercialization. The last few years have seen an increasing demand for new extraction techniques with shortened extraction time, reduced organic solvent consumption, and increased pollution prevention. Under these terms since 2013 the Agro-Food department start research activities in engineering processes to provide solutions in regard to the valuation of food-industry by-products using new eco-processes for selective recovery of high valued molecules which can be used as natural additives in food industry, cosmetics and pharmaceuticals.


Green process,
Process integration,
By-products valorization,
Secondary metabolites

Human resources

  • 1 Professor (teaching and research)
  • 1 Research engineer
  • 1 Technician

Research areas

  • Agro-Industrial by-products valorization
  • Green process development
  • Secondary metabolites extraction
  • Purifi cation / Enrichment

Tools and methodologies

  • Pressurized and supercritical fl uid extractor (Separex)
  • Bioreactor (Applikon)
  • Peristaltic pumps (Masterfl ex L/S)
  • UV-Spectrophotometer (Varian)
  • HPLC-UV (Shimadzu)
  • GC-MS/MS (Varian)

Scientific and professional partnerships


  • Mc Cain
  • Agro-Food and Biotechnology Research Institute “Charles Violette”


  • KU Leuven University (Belgium)
  • TECSE Laboratory, UNCPBA (Argentina)
  • University of Exeter (United Kingdom)


Vauchel P., Galván D’Alessandro L., Dhulster P., Nikov I. & Dimitrov K. (2014). Optimization and pilot scale demonstration of integrated extraction-adsorption eco-process for selective recovery of antioxydants from berries wastes. Separation and Purifi cation Technology. Submitted article.

Galván D’Alessandro L., Dimitrov K., Vauchel P. & Nikov I. (2013). Kinetics of ultrasound assisted extraction of anthocyanins from black chokeberry wastes. Chemical Engineering Research and Design. DOI: 10.1016/j.cherd.2013.11.020.

Galván D’Alessandro L., Vauchel P., Przybylski R., Chataigné G. Nikov I. & Dimitrov K. (2013). Integrated process extraction-adsorption for selective recovery of antioxidant phenolics from Aronia melanocarpa berries. Separation and Purification Technology, 120:92-101.

Galván D’Alessandro L., Kriaa K., Nikov I. & Dimitrov K. (2012). Ultrasound assisted extraction of polyphenols from black chokeberry. Separation and Purification Technology, 93:42-47.


Sylvie Chollet
Team leader

Tel: +33 (3).
@ : sylvie.chollet(at)isa-lille(dot)fr